We are a team of neurologists and neuroscientists, using a variety of interdisciplinary tools including stem cells, bioengineering, genetics, transcriptomics, bioinformatics, gene transfer and gene editing. Our mission is to develop and utilise novel technologies to study and treat neurological diseases.
Research in the Corti lab is aimed at the study of human CNS diseases. We do this by making use of an in vitro model systems that include cerebral and spinal cord organoids. These 3D self-organising neural tissues develop from human pluripotent stem cells and model many key aspects of human CNS. Furthermore, they can model a variety of neurodegenerative disorders. The goal of our research is to understand and treat the mechanisms underlying human neurodegeneration.
We are interested in cellular and molecular treatment of neurological diseases.
Tools: stem cells, iPSC, organoids, gene theray, ASO
Diseases: SMA, ALS, CMT2A, motor neuron diseases, rare neurological diseases.
Dr. Corti is the PI of Neural Stem Cell Lab and Full Professor in Neurology at the University of Milan. She is the Director of Neuromuscular and rare diseases unit, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico.
She is a researcher in the Neuroscience field, committed to studying the pathogenesis and stem cell/molecular therapies for the treatment of motor neurons diseases, in particular Amyotrophic Lateral Sclerosis (ALS), Spinal Muscular Atrophy (SMA) and Spinal Muscular Atrophy with respiratory distress type I (SMARD1).
Since 1994 and after Medical Degree (1997, magna cum laude), Dr Corti has been involved in the research about neurodegenerative diseases and stem cells in the Department of Neurological Sciences of the University of Milan, where she obtained her education as researcher.
After Board Certification in Neurology, she obtained a PhD in Molecular Medicine at the University of Milan. Since 2004, up to now, she has worked first as research collaborator, then as Assistant Professor at the University of Milan.
In 2015 she become associate professor of neurology at Unimi.
In 2023 she become Full Professor of Neurology at University of Milan and Director of Neuromuscular and Rare diseases Unit at IRCCS Foundation Ca' Granda Ospedale Maggiore Policlinico.
She is a member of the Board of the PhD School of Molecular Medicine, of the Dino Ferrari Center Scientific Committee, FRRB and Foundation Ca' Granda Ospedale Maggiore Policlinico Scientific Commitee.
The scientific results of Dr. Corti, basic and clinical research have been published in high citation rating peer reviewed journals.