Research & Initiatives

Neurodegenerative diseases are highly disabling and fatal disorders, often without a cure, that place a huge burden on patients and their families and have a significant impact on society. There is urgent need to find effective treatment for these conditions.

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Our research is focused on studying all aspects of neurodegenerative diseases like spinal muscular atrophy (SMA) and amyotrophic lateral sclerosis (ALS). 

 

Our group creates synergistic,  programs for target discovery and functional analysis in an intellectual, collegial and stimulating environment.

 

 University of Milan and Foundation IRCCS Ca' Granda offer an unparalleled location for this initiative because it currently houses, in close proximity, world-class research and clinical groups. These include scientists engaged in the study of neuronal function, relevant aspects of stem cell biology and in vitro and in vivo models of human diseases. These scientists work with internationally renowned clinicians experienced in clinical trials for neurological diseases, committed to apply into their programs the latest findings from basic research and able to provide advice about the feasibility of therapeutic approaches for humans.

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Areas of Investigation

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Molecular therapies for neurodegenerative diseases

Neural stem cell transplantation as therapeutic approach

Reprogramming neuronal identity in vitro and in vivo

Modeling human neurological disease in vitro